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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cae56c40347b9589bd05f87b43659f93c4c0aed6b0940c13473db9ad8214ffa' 
  AND token = 'kwEYkgRiwVQxAoA+5sbO7NA8PAamE0sjIwUYdOoCkfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}