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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1081f44a2aa2077794d12be1d2b059820f9c0ac36c8c0db50597faa89112f9' 
  AND token = 'TJ461kT/aaFV+zv5PFm/QeiXy48omhrJbvJGskm1lmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}