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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c4e949352fb53b78b7b210696b57746071453b06b6db02a721073954e555db' 
  AND token = 'eKrZa6JlaL7AQ+M3KXDignLhTcJZtvJRH7NeegXM/pI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}