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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725d1dd1fd9bf74ad9a5793cd77d81257255ffc71ba02e6548764433f0321ab2' 
  AND token = '3Wwe22E9TEc2HLWYNsgtSmPy3rlbHKLu0mI8S7snD5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}