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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45acb2fe01cb2fcb36b271ae0db6ccdabbceb92247f70e0e2320d17503a969bf' 
  AND token = 'aiSP3DiQbx8w2UZ/mZngkLn9Gzg2vMNE6WoHs8/avB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}