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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d79bda592f64d8dbe0a7e29281d1975070c48a031497d6d0c6073e2455e9123' 
  AND token = 'T+0QBN/zRgKdHBX7LUIt3oI9PgjPr6YXtxPcgqQkH48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}