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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cbad9f82ffb5f5769495097d88df589e0d18a38b00d64a74bd0a60301402456' 
  AND token = 'HIgTkVpCxtu1kEUtKHHyVGOPPeANlwMgAi3n58cG2c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}