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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78783d4b3bc1a01da706df2bbf2d4c58bae4d2122c35084dacde0bf3f7a63c61' 
  AND token = 'YZjSBHC59hxWh9K6T+5TzE5px0DPH11FAWFsVSjTA74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}