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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06cb9ae6e129a44e6c66f61a9d8fa749e2908dd158b9e3bd2e29cf023ab237fc' 
  AND token = '000CsJNTDULzgFR51lLdswCwtZV428raKk8WUZG9x5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}