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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db2a951b3d4ee715233db8303976e3b13970d780ce8c5b4600767c86923c35b' 
  AND token = 'ysyaJ4lZaJGkYxEX/87TABfJRNeXhm+dZCBx8uEsAs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}