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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5accc6e03a31edf037e91f89d236c86f135dd048ded2fe5745165eef42d75c' 
  AND token = 'y+GFm+EetYXS2B2HUn3/KVehQyiBzlFWM1irg7w9sPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}