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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad7e67896cbed4ceb0584aee2f5f02be8b72d5dc8ab7b31197fb6549664014d' 
  AND token = 'KHQ4xAdm1GQuCADG7haT6PvuDMfnKLpAk38VWRCLM7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}