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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ddbc851ebc6f34efbda2dc6e08ec2d60ef34d85600e4304eee79ac2d9572134' 
  AND token = 'GrOCsUZKco+CsZhHA5iP9R/eEAtcn0DJVPzclfdMJ4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}