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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afbcb8a29b45e064eab820946df38b9b51353582a1c3310bdc7e6aea588beacc' 
  AND token = 'FNnIk6kgpB8dFPUN7a9c9xNQhGTB6oU6QQKh0+7ndvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}