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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce90a9eb47677d151c171db0f8891c5082975e9c82849462bfb05054f1a92c50' 
  AND token = 'M4t//gjCPalsINtahIdNuTqFMTrmTCUjIKGwbz6SDLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}