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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6902e95f885618db3d25a50833d9f9685f65700cf1c2671081ef5c0586e2faad' 
  AND token = 'HcPizdNmm0VKQTSyVVRjA3dVgSJZm5bzCZcV6ebeYBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}