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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac50e88de6b2e89893f0d9e32ccadc9e7313f16d62f889a84b338b35775ef65' 
  AND token = '1DTQ6Z13ort98PuFZ8fCGUfkWk2IyaKGt1S1bVC7soM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}