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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0ca68d9614fa82605ebb05ecbd67c20fe3b9d0a172c1b3555fe33fa2df3903' 
  AND token = 'HyvE3kvEiHy33CDb5awUeAeH9cLCyCCvTZIM4FAJ9aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}