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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '956fb9f3954135c219673baaf3598c2409cdb59b42cc2ffbbe0b4e36a545c251' 
  AND token = 'hMQBOPhoGaYL9ExKPbVMP5u3iRWTvGOX1AncrPyVyX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}