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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cedd187244ce4d004362641d0e0803cdf8c7b10498b1aa6f35236de46e8240fe' 
  AND token = 'DwLr0v9e17maMd2BYhdCirwHLQTsU9rnMa5riM+QAh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}