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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376152e1d51baa3c36bc19b8c10a5ec2663e6d159b1f70aca55c06891f3a569d' 
  AND token = 'iGrV+mJPVPwcmTK/xP7vNW3Hybvhmw102UnAjs31Fnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}