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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42f03e4689dc8b78010b9b920905a39b4edb6c4340c1c60bf288a3a87f17809' 
  AND token = '/2Xxn8S1V7NgOtHAW1xrCGaj/rvFeWuJWKkVMLHUzFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}