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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b348b0760d4c1db6a02ec6f4fc12224502dfc55500d187486747c7bc271de49' 
  AND token = 'O3Kb5hLeVUrHCxAHCt+opJeooAa7XXhFYl38NQYVBw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}