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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b8ce412197a5bafd42c3cf22fe263768c3f6ebb2f84efef68fdcae0ebe8335' 
  AND token = 'HUluH75/yhgnIbHc9/iy2njyOsmAzsQ9oA6I6Sqf6a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}