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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '015fe70ab5a0bd316c858f729afdb98622cb166d93d1f097063c32b672858609' 
  AND token = 'OWoZ1cVw6WfXl5KJxGrhRX+L8y4e1esZUHnwkA9sYq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}