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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec2ca222c9e109371b03eb524d9be8c574b3057dc9d9f515f4ce9d21118ce12' 
  AND token = 'kc/bj7VKIkX1antJosyqnXFhZj0UAUt0GugaLWR3e+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}