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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916204918bb6494206821f0c2adc2d8bb2a2abed25110139c1e9c42f0a3e3c49' 
  AND token = '1vIGvVOHPRilcxB/TdYTUIKmwEG6Az5eqvRnUuZobtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}