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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e242dcf2ac712d284d8d6f06e2e4b9cf77629194c09a85e73f3671c4784406' 
  AND token = 'npPJyN323lakug/x0BS5H4BjT5QJzx9p6wPB8Fw/XtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}