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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eec1f15dfb844061f311cbc1ba1edf3b0d5026a7f8d129ed4545330cd91fe04a' 
  AND token = 'tTC4ESh9y1wuZsjvPlRm2NAh1qEK2+5mxMyhpCl52o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}