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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d6828228359007644419bd78753958fe28c38ee4237c1b22e4aa5e6695ad17' 
  AND token = '2liN2SDV5Uqocjf8d0k2zjQ+n4JLcmzWkYRzWE5jkWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}