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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287cfbac389a1a5ec6028a9eb19fc5f8fddd268bbbc0e984f234f108130297cc' 
  AND token = 'b5G2f7zege5PpPRcJfJBkbW0JAwYovqNLYkAQLnl874=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}