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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3aa722d7b0d5367d7290e505c38180736df38a00bf12dd20809a69c92a3893a' 
  AND token = 'A5/CBALNFLURGpfItBL1uEuRsJLcUy/KL8Su1wq0jC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}