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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4165f35db91fb9d6b9888cff9368234333f1fc1bdc924c1525dd72c1cd0a14c9' 
  AND token = 'YA2nQZs8BSlpB6N2oi1Oqy5D8puPhO5xAaAtZ8HU1sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}