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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18cea5d25e4ad7ed65face92e393f6f55d2320956637f29ad14dd3f5afb0d380' 
  AND token = 'FjdL+znUWYKJUpXjlUkBp2Bzclo/pMFzlm2KjepiOGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}