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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25def7a702a7193543f65f10dad7b6d00513022706d9f5e436a94577c98a99eb' 
  AND token = 'Ab3HkV5railuw75TiqWw8/Rr4ndmSt4cNda1hmrc4Ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}