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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23353fb4863ec0bcc4fdc2756f791ff1e191980d49b1b09b00c925b82742ebe0' 
  AND token = 'Pl7HHp/LBVJ+2VL+9grAVUf8R0r1bVr2pd7hRaVMtcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}