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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2105eba77e2c3f0b3ab6da2b73998b42feb7eecb7e6d19276b4868fe09e307' 
  AND token = 'PRpWeiSnccBqa2XYhYIMRYZyWDq52a0zdPe9eWdG5+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}