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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc293d1a998d8db0db6e89ddeaf0ab667221d0557c4e384437fc4d4f92ebcd21' 
  AND token = 'oeAKmq4NVid6gtrSu8lT8Boz3GyoxcOAYpzQwZUEaaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}