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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467b266b965a0b98180b6ad25e54ae3aa3460642d7faa0aeca1500361a365126' 
  AND token = 'HskFYyjKxdQq69CQTKZKosMrNiRiXhY8sM2LQ/RBHFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}