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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d846c0f7bf85dec7660bef07ce0c727158984567966a8533840ad26526e0e87' 
  AND token = 'OOqr8ro6tPyNl3U/bXZCk5eYmKDTbtuCCZ8z/hwuTvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}