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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d573a977abf0fe0d4f635d165847296b9b99824c67adadaf3aee64e4e0f3a9b' 
  AND token = '/VCWXbPkVBzaqXuCbXBtSFsk4AGIWCaXua8dk0a1gLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}