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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa4cf449cb052248aa8cfe84aa2e48c4d23d6123bc22d0aeedc9efe812686c4' 
  AND token = 'pB7XnMPkHdHw5OE4ZhgrhcfS+ic4qM/SS2vbOzcs/vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}