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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84bc3648ccb3014f1b799b441de94e14241914e7c1903705ab56663199d29de5' 
  AND token = 'yBQcSFV7FiF+SRhfiO8soHwTSn/hvGoO3Tmr9xvBPLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}