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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '502de1fb255d5234cc31a2a3c67e2676453a657dcc2dc2fe95e0ee0ba8ef2179' 
  AND token = '6HysDtLUD3gi5vjydICmTd5klqA5hjxDrRDL+x8nSgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}