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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325f12ebc1189d1c26520a6e38d8b5583629b87ac6a156432aedd05d6de8aa5f' 
  AND token = 'pP52vXnEJm4Jy+KRkinWVRVaIXqrL5kpZ5kHDQlytOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}