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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6171fbfee7808d70f61b8eea943e63758c383e9423f4203e552a077510ef7d8' 
  AND token = 'Z0TlvPA2zzFhrTgJSY+vkay291vdBZ1IvVXnKre43ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}