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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2a311d5b79dbbecec1637b6c370fe7d6f45731e784abb0e530ba4c3b141111' 
  AND token = 'bLUQa+O8xraDREmbGdIfEq0S5UyYnbqbTmJLv/ak1eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}