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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e395360b4c6d81ea1a3ff63baa0f26a89b61bc9c18d9e73155b70998fa262d88' 
  AND token = 'k0f3xZ+r8Ix9xkej5AP46E0voYMnHS0FqIphFKkdcys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}