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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f13022d9c4271aba8980d8181b921e93dfe7d1ca74ee13ecaccce6895b98c25' 
  AND token = '72kQv8fMUGsv4RKs5ry8MWoWGw6IC9IlWLhlhI5v4JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}