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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd44573086e108f7c457b003e9864bd275a03dcff5516846d06ad781d1f69c98' 
  AND token = '7yy+5iu0anNwoQgBOb4W4BL9fcBgQh7K0fDhuz/1nu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}